Missed a Zepbound, Mounjaro, Ozempic or Wegovy Dose? What to Do

Take a missed Zepbound dose as soon as possible, within 4 days (96 hours) of its due day (Zepbound prescribing information, section 2.3). Later than that, skip it and inject on your usual day. Mounjaro follows the same rule and Ozempic allows 5 days; US Wegovy allows it only while the next dose is over 48 hours away.

Key facts

• Two doses must be at least 72 hours apart on Zepbound and Mounjaro, and more than 2 days apart on Ozempic in the US (Zepbound, Mounjaro and Ozempic labels).
• In the UK, Ozempic and Wegovy doses must be more than 72 hours apart, and a late Wegovy dose follows Ozempic’s window (Ozempic and Wegovy UK prescribing documents, section 4.2).
• Never double up to catch up; the UK leaflets say "Do not use a double dose to make up for a forgotten dose" (Mounjaro and Ozempic leaflets).
• A forgotten daily Wegovy, Ozempic or Rybelsus tablet is skipped, with the next taken the day after; Foundayo has its own rule (Wegovy and Foundayo labels).
• When 2 or more Wegovy doses in a row are missed, the US label restarts the dose climb from a lower dose (Wegovy label, section 2.4).

What to do by how late you are

Past each window, skip the missed dose, take the next one on your usual day and carry on weekly from there (Zepbound label, section 2.3). In the UK, each Summary of Product Characteristics (SmPC), the prescribing document, gives Mounjaro and Ozempic the same windows as the US labels (Mounjaro SmPC; Ozempic SmPC).

To get the deadline to the hour from the time of your last shot, use the missed dose guide, which applies the US rules or, if you choose, the UK ones.

How late can I take Wegovy?

In the US, a missed Wegovy injection can still go in while your next dose is more than 2 days away. The Medication Guide’s test is whether "the next scheduled dose is more than 2 days away (48 hours)" (Wegovy prescribing information, section 2.4 and Medication Guide). Ozempic, the same drug, counts forward from the missed dose instead and allows 5 days (Ozempic label, section 2.1).

On a regular 7-day week the two rules land in almost the same place, because 7 − 2 = 5. They part when your next dose is due sooner, for example after you have moved your injection day. If your next Wegovy dose is due 5 days after the missed one, the US window closes at 3 days late (5 − 2).

The UK Wegovy SmPC counts forward like Ozempic: a missed dose can go in within 5 days, and after that it is skipped (Wegovy SmPC, section 4.2). Follow the rules for the product and the country your pen came from.

How close together can two doses be?

Each label, or for US Wegovy its Medication Guide, sets a minimum gap between two injections. The same gap applies when you move your injection day on purpose.

The UK column comes from section 4.2 of each SmPC (Mounjaro, Ozempic, Wegovy). The UK Ozempic and Wegovy SmPCs add that once you pick a new day, you carry on weekly from it.

Say you inject on Sunday and want Thursday instead. Thursday is 4 days (96 hours) after Sunday, which clears every minimum gap, so you inject on Thursday and keep Thursday from then on. For Monday, wait until the Monday 8 days after your last Sunday dose, because the Monday right after it is only 1 day on.

A dose taken one day early is a day change too. Six days after your last dose clears every minimum, and that day becomes your weekly day. The labels set a minimum gap and no maximum, so a move to a later day makes that week’s dose late, and your missed-dose window still applies.

When picking a new injection day and time, any hour works, because each label allows injection at any time of day (Ozempic label, section 2.1; Zepbound label, section 2.4).

If you have missed 2 weeks or more

Among the weekly shots, only Wegovy’s labels have a rule for a longer gap. In the US, 2 or more missed doses in a row mean a restart at a lower dose, to lower the chance of stomach side effects (Wegovy prescribing information, section 2.4). Its Medication Guide says to contact your healthcare provider about how to restart. The UK SmPC says that if more doses are missed, "reducing the starting dose for re-initiation should be considered", and gives no number (Wegovy SmPC, section 4.2). A restart at a lower dose then climbs back up the dose ladders for each brand step by step.

The Ozempic, Zepbound and Mounjaro labels set no rule for a run of missed doses, so ask your prescriber what dose to restart on before the next injection. Half the semaglutide from a shot is gone in about a week, and half the tirzepatide in about 5 to 6 days (Ozempic label, section 12.3; Zepbound label, section 12.3).

For the share left 1 to 5 weeks after the last shot, the GLP‑1 Plotter has a washout table. Your own gap shows up on the level curve that Pensday draws from the shots you log. A break you plan is a taper rather than a missed dose, and tapering off semaglutide follows its own steps.

If you injected an extra dose

If you inject an extra dose, "call your healthcare provider or Poison Help line at 1-800-222-1222 or go to the nearest hospital emergency room right away" (Zepbound, Mounjaro, Ozempic, Wegovy Medication Guides). Every US guide words it that way, and Wegovy’s adds that too much can cause "severe nausea, severe vomiting and severe low blood sugar".

In the UK, talk to your doctor straight away after too much Ozempic or Wegovy; both leaflets warn of nausea (Ozempic and Wegovy leaflets). After too much Mounjaro, talk to your doctor immediately, because it can cause low blood sugar and make you feel or be sick (Mounjaro leaflet).

Missed a daily GLP‑1 pill

For a missed Wegovy tablet, Ozempic tablet or Rybelsus tablet, skip it and carry on with the next day’s tablet (Wegovy label, section 2.4; Rybelsus and Ozempic tablets label, section 2.1).

Foundayo is the exception. Take a missed Foundayo tablet as soon as possible, and do not double up the next one (Foundayo label, section 2.3). After 7 or more missed Foundayo doses in a row, the climb restarts at a lower dose.